Fig. 1.

Effect of shiikuwasha extract or grape extract supplementation on dexamethasone-induced changes in hind-limb muscle weight. Rats were fed an extract-supplemented diet for 19 days. During the last 5 days of feeding, the DEX, DEX + SE and DEX + GE groups were injected with dexamethasone, while the CTL group was injected with an equal volume of saline. After 5 days of dexamethasone treatment, hind-limb muscles were collected and weighed. a Gastrocnemius muscle, b tibialis anterior muscle, c soleus muscle, d extensor digitorum longus muscle. CTL control, DEX dexamethasone, DEX + SE dexamethasone + shiikuwasha extract, DEX + GE dexamethasone + grape extract. Values are mean ± SEM (n = 5 or 6). *P < 0.05 CTL versus DEX (student’s t-test), ^† P < 0.05 versus DEX (Dunnett’s test)