Table 2.
Effects of shiikuwasha or grape extract supplementation on dexamethasone-induced changes
CTL | DEX | DEX + SE | DEX + GE | |
---|---|---|---|---|
Body weight (g) | ||||
Before DEX treatment | 766.5 ± 32.8 | 757.6 ± 25.1 | 757.2 ± 20.5 | 777.0 ± 46.1 |
After DEX treatment | 735.0 ± 31.9 | 638.5 ± 20.1* | 654.5 ± 19.8 | 663.5 ± 37.6 |
Body weight loss (g) | 31.57 ± 2.84 | 119.06 ± 8.68* | 102.74 ± 10.66 | 113.58 ± 10.68 |
Average dietary intake (g) | ||||
7 days before DEX treatment | 22.4 ± 0.30 | 21.6 ± 0.72 | 19.4 ± 1.01 | 20.94 ± 0.51 |
5 days during DEX treatment | 13.1 ± 0.14 | 11.52 ± 0.91 | 9.33 ± 0.86 | 11.14 ± 1.12 |
Serum insulin (ng/ml) | 0.56 ± 0.13 | 12.03 ± 2.54* | 8.42 ± 1.42 | 14.06 ± 2.98 |
Values are mean ± SEM (n = 5 or 6)
CTL control group, DEX dexamethasone treatment group, DEX + SE dexamethasone treatment and shiikuwasha extract supplemented group, DEX + GE dexamethasone treatment and grape extract supplemented group
* P < 0.05 CTL versus DEX (student t-test)