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. 2016 Jun 22;10:68. doi: 10.3389/fnana.2016.00068

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Copyright © 2016 Dyster, Mikell and Sheth.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tractographic representation of a subcallosal cingulate fiber bundle optimal for DBS. Probabilistic tractography and similar techniques make it possible to evaluate patient-specific network connectivity when creating surgical plans. Using this information, physicians are able to select individualized stimulation targets at points where critical white matter tracts intersect. Red: forceps minor. Blue: uncinate fasciculus. Yellow: cingulate bundle. ACC, anterior cingulate cortex; Amg, amygdala; Cingulum B., cingulum bundle; Forceps M., forceps minor; MCC, middle cingulate cortex; mF10, medial frontal (Brodmann area 10); nAc, nucleus accumbens; SCC25, subcallosal cingulate cortex (Brodmann area 25); Th, thalamus; Uncinate F., uncinate fasciculus; vSt, ventral striatum. Reprinted from Riva-Posse et al. (2014); Copyright with permission from Elsevier; permission conveyed through Copyright Clearance Center, Inc.