Table 2. IKZF1 and JAK2 status of kinase fusion-positive patients in this study.
| Kinase fusion |
IKZF1 |
JAK2 |
||||
|---|---|---|---|---|---|---|
| WT | Deletion | ND | WT | Mutation | ND | |
| P2RY8-CRLF2 | 6 | 3 | 1 | 8 | 1a | 1 |
| IgH-CRLF2 | 0 | 1 | 1 | 0 | 1b | 1 |
| CSF2RA-CRLF2+IgH-EPOR | 0 | 1 | 0 | 1 | 0 | 0 |
| EBF1-PDGFRB | 0 | 5 | 1 | — | — | — |
| ATF7IP-PDGFRB+P2RY8-CRLF2 | 0 | 1 | 0 | 1 | 0 | 0 |
| ATF7IP-PDGFRB | 0 | 0 | 1 | — | — | — |
| PAX5-JAK2 | 0 | 1 | 0 | — | — | — |
| OFD1-JAK2 | 0 | 1 | 0 | 1 | 0 | 0 |
| IgH-EPOR | 0 | 1 | 1 | — | — | — |
| SNX2-ABL1 | 0 | 0 | 1 | — | — | — |
| ZMIZI1-ABL1 | 0 | 0 | 1 | — | — | — |
| ETV6-ABL1 | 0 | 1 | 0 | — | — | — |
| NCOR1-LYN | 0 | 1 | 0 | 1 | 0 | 0 |
Abbreviations: ND, not determined; WT, wild type.
a
R683S mutation was identified.
b
Both R683S and R683G mutations were identified in this patient.