Table 3.
Change in 24-hour albuminuria levels and other relative indicators.
| Week | Treatment group | Control group | p value | |
|---|---|---|---|---|
| (n = 47) | (n = 44) | |||
| Albu (mg/24 h) | 0 | 85.30 (66.00, 176.30) | 90.50 (67.78, 124.68) | 0.940 |
| 4 | 61.50 (49.00, 110.20)∗ | 89.00 (61.78, 125.25) | 0.086 | |
| 8 | 51.00 (37.00, 90.00)∗ | 70.00 (53.00, 100.93)∗ | 0.031 | |
| 12 | 41.40 (29.00, 68.00)∗ | 47.65 (36.30, 100.53)∗ | 0.045 | |
|
| ||||
| FBG (mmol/L) | 0 | 7.40 (6.70, 7.80) | 7.40 (6.80, 7.80) | 0.883 |
| 4 | 6.80 (6.10, 7.50) | 7.00 (6.15, 7.60) | 0.343 | |
| 8 | 6.90 (6.00, 7.40) | 6.80 (5.85, 7.60) | 0.899 | |
| 12 | 7.00 (6.30, 7.6) | 6.75 (6.10, 7.53) | 0.775 | |
|
| ||||
| 2 h PBG (mmol/L) | 0 | 9.52 ± 1.27 | 9.58 ± 1.05 | 0.877 |
| 4 | 9.48 ± 0.28 | 9.49 ± 0.25 | 0.988 | |
| 8 | 9.37 ± 0.27 | 9.45 ± 0.26 | 0.836 | |
| 12 | 9.28 ± 0.29 | 9.42 ± 0.34 | 0.952 | |
|
| ||||
| TPU (g/24 h) | 0 | 0.20 (0.10, 0.30) | 0.20 (0.20, 0.30) | 0.943 |
| 4 | 0.10 (0.10, 0.20)∗ | 0.10 (0.10, 0.30)∗ | 0.792 | |
| 8 | 0.10 (0.10, 0.20)∗ | 0.10 (0.10, 0.20)∗ | 0.936 | |
| 12 | 0.10 (0.10, 0.20)∗ | 0.10 (0.10, 0.20)∗ | 0.633 | |
|
| ||||
| A/C (mg/mol) | 0 | 20.70 (11.00, 30.50) | 19.45 (7.83, 30.63) | 0.952 |
| 4 | 16.30 (8.10, 25.00)∗ | 16.10 (6.05, 23.45)∗ | 0.724 | |
| 8 | 15.00 (7.20, 20.60)∗ | 11.15 (5.40, 20.80)∗ | 0.380 | |
| 12 | 10.10 (5.60, 17.00)∗ | 8.9 (5.30, 19.23)∗ | 0.662 | |
Data are expressed as the mean ± SD for normal distribution. Nonnormally distributed values are presented as median (interquartile range). p values represent the treatment group versus the control group. ∗ represent p < 0.05 versus baseline (week 0), paired t-test for normal distribution or Wilcoxon matched-pairs signed-rank test for nonnormal distribution. Albu, albuminuria; FPG, fasting plasma glucose; PBG, postprandial blood glucose; TPU, total proteinuria; A/C, urinary albumin to creatinine ratio.