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IC50 of PTK inhibitors.
| IC50 (nM) | Dasatinib | Gefitinib | Imatinib | Staurosporine |
|---|---|---|---|---|
| Src | 12 ± 0.96 | >5000a | —b | 310 ± 28 |
| Fyn | 26 ± 2.2 | >2000a | >10000a | 260 ± 19 |
| EGFR | 1400 ± 110 | 22 ± 2.4 | —b | 2300 ± 820 |
aNot determined due to poor curve fitting of weak inhibitors. bInhibition was not observed.
