Table 1.
Training Phase No ALERT (n=126,790) | Training Phase ALERT (n=29,317) | Validation Phase No ALERT (n=127,078) | Validation Phase ALERT (n=29,029) | |
---|---|---|---|---|
CHARACTERISTICS | ||||
Age | 55·2 ± 21·9 | 63·7 ± 18·1* | 55·3 ± 22·0 | 64·0 ± 18·1* |
Female sex | 81,153 (64%) | 15,086 (51·5%)* | 81,062 (63·8%) | 14,868 (51·2%)* |
Cancer diagnosis | 10,835 (8·5%) | 4,886 (16·7%)* | 10,681 (8·4%) | 4,508 (15·5%)* |
CABG | 438 (0·8%) | 500 (1·7%)* | 461 (0·4%) | 418 (1·4%)* |
APACHE score | 46·4 ± 20·6 | 63·8 ± 27·5* | 46·1 ± 20·1 | 65·0 ± 27·9*† |
Trauma | 5,520 (4·4%) | 1,476 (5·0%)* | 5,990 (4·7%) | 1,384 (4·8%) |
Cardiac disease | 28,819 (22·7%) | 8,901 (30·4%)* | 27,983 (22·0%) | 8,469 (29·2%)* |
Cerebrovascular disease | 5,833 (4·6%) | 1,147 (3·9%) | 5,649 (4·5%) | 1,183 (4·1%) |
COPD | 7,402 (5·8%) | 3,136 (10·7%)* | 8,032 (6·3%) | 3,579 (12·3%)* |
CKD | 5,577 (4·4%) | 2,167 (7·4%)* | 5,963 (4·7%) | 2,035 (7·0%)* |
OUTCOMES | ||||
ICU length of stay | 1·4 ± 1·4 | 3·4 ± 4·2* | 1·3 ± 1·3 | 3·4 ± 4·2* |
Hospital length of stay | 3·5 ± 4·0 | 6·7 ± 6·9* | 3·5 ± 3·6 | 6·4 ± 6·3*† |
Number of Ventilator days | 1·9 ± 1·4 | 3·8 ± 3·9* | 1·7 ± 1·2 | 3·7 ± 3·7 |
Angus criteria | 6,242 (4·9%) | 7,856 (26·8%)* | 6,384 (5·0%) | 7,888 (27·2%)* |
Severe Sepsis | 0 (0%) | 21,829 (74·5%)* | 8838 (9·8%)† | 20,191 (69·6%)*† |
Mortality | 233 (0·2%) | 1,539 (5·2%)* | 264 (0·2%) | 1,684 (5·8%)* |
different within phases
different across phases when comparison is made by ALERT status
CABG=coronary artery bypass grafting; COPD= chronic obstructive pulmonary disease; CKD=chronic kidney disease