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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Am J Med. 2016 Mar 24;129(7):688–698.e2. doi: 10.1016/j.amjmed.2016.02.037

Table 4.

Test characteristics of SIRS/OD alert to predict severe sepsis and mortality

DERIVATION PHASE B (95%CI) VALIDATION PHASE B (95%CI)
Severe Sepsis
Sensitivity 1·0 0·99
Specificity 0·94 0·94
Area under the curve 1·0 0·96
LR+ 17·9 15·2
LR− 0 0·01
Mortality
Sensitivity 0·87 0·86
Specificity 0·82 0·82
Area under the curve 0·84 0·84
LR+ 4·8 4·9
LR− 0·16 0·16

LR+ = positive likelihood ratio of the SIRS/OD alert as a test; LR− = negative likelihood ratio of the SIRS/OD alert as a test.