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. 2016 Jun 14;7(3):e00618-16. doi: 10.1128/mBio.00618-16

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Copyright © 2016 Rivera-Hernandez et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Antigen-specific IgG response in serum samples from BALB/c (A) and humanized plasminogen AlbPLG1 (B) mice at day 35 (n = 10). Antigens used to coat ELISA plates are displayed. IgG titers in antigen-immunized groups (M1, Combo#5, J8-ADI, or ΔGAC-ADI) were compared to titers in PBS-immunized mice (open circles) and found to be significantly different (P < 0.0001) using a two-tailed Mann-Whitney U test. Each symbol represents the value for an individual mouse. The bars show the geometric mean titer (geomean titer) with 95% confidence interval (95% CI). α-M1, anti-M1 antibody.