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editorial

. 2016 May 16;15(10):1311–1312. doi: 10.1080/15384101.2016.1161994

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© 2016 The Author(s). Published with license by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — SRF and IL6 are essential for YAP induction of MaSC-like properties in basal-like breast cancer. TAZ is involved in lineage switching from luminal to basal/myoepithelial cell type. YAP is involved in endowing mammary stem cell properties. YAP mediates this function by binding SRF to induce the expression of mammary stem cell signature genes specifically in basal-like breast cancer, but not in luminal-type breast cancer.