Table 1. Detection of the metabolite variation between the VdCYP1 deletion strain and the wild-type strain using the UPLC-Q-TOF method.
| Description | Matching ID# | WT/ΔCYP-1 | WT/CYP-2 |
|---|---|---|---|
| Sulfacetamide | HMDB14772 | 26.126 | 39.588 |
| 1-Methoxy-1H-indole-3-acetonitrile | HMDB40973 | Infinity | 1.190 |
| Sinalexin | HMDB32026 | 19.442 | 1.248 |
| Penmacric acid | HMDB29436 | 13.082 | 1.260 |
| Alloxan | HMDB02818 | 8.036 | 1.092 |
| Pomolic acid | HMDB35106 | 7.610 | 1.546 |
| Sonchuionoside C | HMDB35212 | 4.565 | 1.197 |
| Eszopiclone | HMDB14546 | 4.000 | 1.201 |
| Zopiclone | HMDB15329 | 4.000 | 1.121 |
| 1-(1-Propenylthio)propyl disulfide | HMDB33041 | 3.945 | 1.041 |
| (E)-1-Propenyl 1-(propylthio)propyl disulfide | HMDB33072 | 3.945 | 2.073 |
| 2, 4, 6-Triethyl-1, 3, 5-trithiane | HMDB40262 | 3.945 | 1.071 |
| 4-Phenylpyridine | HMDB33123 | 2.571 | 1.453 |
| Capsiate | HMDB34780 | 1.953 | 2.168 |
#The metabolite detection involved searching 3 databases, including the Human Metabolome Database (http://www.hmdb.ca/), the KEGG database (http://www.kegg.jp/kegg/), and the ChEBI database (http://www.ebi.ac.uk/chebi/).