Table 2. Subsequent risks of senile cataract in MGUS, MM, Waldenström, and AL amyloidosis patients.
MGUS | MM | Waldenström | AL amyloidosis | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | |||||
All | 1711 | 1.80 | 1.71 | 1.88 | 891 | 1.70 | 1.59 | 1.81 | 237 | 1.85 | 1.63 | 2.11 | 338 | 2.31 | 2.07 | 2.57 |
Gender | ||||||||||||||||
Men | 771 | 1.80 | 1.67 | 1.93 | 439 | 1.80 | 1.64 | 1.98 | 132 | 1.91 | 1.60 | 2.27 | 161 | 2.50 | 2.13 | 2.92 |
Women | 940 | 1.80 | 1.68 | 1.91 | 452 | 1.61 | 1.46 | 1.76 | 105 | 1.78 | 1.46 | 2.16 | 177 | 2.16 | 1.85 | 2.50 |
Age at diagnosis (years) | ||||||||||||||||
<60 | 32 | 2.04 | 1.40 | 2.89 | 30 | 3.17 | 2.14 | 4.53 | 5 | 3.31 | 1.04 | 7.79 | 40 | 7.30 | 5.21 | 9.95 |
60–79 | 967 | 1.88 | 1.76 | 2.00 | 536 | 1.77 | 1.63 | 1.93 | 137 | 2.10 | 1.77 | 2.49 | 215 | 2.29 | 1.99 | 2.62 |
80+ | 712 | 1.68 | 1.56 | 1.81 | 325 | 1.53 | 1.37 | 1.71 | 95 | 1.55 | 1.26 | 1.90 | 83 | 1.77 | 1.41 | 2.19 |
Subtype | ||||||||||||||||
Senile incipient cataract (H25.0) | 282 | 1.80 | 1.59 | 2.02 | 151 | 1.64 | 1.39 | 1.93 | 43 | 1.93 | 1.40 | 2.60 | 61 | 2.59 | 1.98 | 3.33 |
Senile nuclear cataract (H25.1) | 111 | 1.75 | 1.44 | 2.11 | 53 | 1.45 | 1.08 | 1.89 | 16 | 1.70 | 0.97 | 2.76 | 15 | 1.70 | 0.95 | 2.81 |
Other senile cataract (H25.2, H25.8) | 28 | 1.88 | 1.25 | 2.71 | 20 | 2.11 | 1.29 | 3.26 | 3 | 1.36 | 0.26 | 4.02 | 10 | 4.20 | 2.00 | 7.76 |
Senile cataract, unspecified (H25.9) | 1290 | 1.80 | 1.70 | 1.90 | 667 | 1.73 | 1.60 | 1.86 | 175 | 1.86 | 1.60 | 2.16 | 252 | 2.26 | 1.99 | 2.56 |
MGUS: Monoclonal gammopathy of undetermined significance; MM: Multiple myeloma.
O = Observed cases; SIR = Standardized incidence ratio; CI = Confidence intervals.
Bold type: 95% confidence interval does not include 1.00.