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The figures were prepared by a semilogarithmic plot of percent remaining activity vs incubation time. Microsomal reaction mixtures were pre-incubated for 20 min without (⚫) or with plumbagin at 0.5 μM (
), 1 μM (
), 2 μM (
) in humans or plumbagin at 0.2 μM (
), 0.5 μM (
), 1 μM (
) in rats. Each data point represents the mean of quadruplicate determinations.
