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. 2016 Jun 22;6:28482. doi: 10.1038/srep28482

Figure 5. Sigmoidal auto-activation kinetics curve of CYP3A2 by various concentrations of plumbagin (0 Inline graphic, 1Inline graphic, 2Inline graphic, 5 Inline graphic, 10 ♦ μM) in rat liver microsomes.

Figure 5

Midazolam was used at concentrations of 2.5, 5, 10, 20, 40 and 80 μM. Insets show the corresponding Eadie-Hofstee plots for CYP3A2 kinetic profile.