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. 2016 Jun 22;6:28556. doi: 10.1038/srep28556

Figure 1. Viral hepatitis is associated with increased TREM1 expression and sTREM1 release.

Figure 1

(A) Increased sTREM1 concentrations in blood plasma from patients with hepatitis B (HBV; n = 34) or hepatitis C virus infection (HCV; n = 29), as compared to healthy control subjects (n = 17). (B) Increased sTREM1 concentrations in blood plasma from C57BL/6 mice during acute hepatitis caused by LCMV-WE infection. (C) Increased sTREM1 concentrations in urine from C57BL/6 mice during acute hepatitis caused by LCMV-WE infection. (D) Increased expression of TREM1 RNA in infected livers of C57BL/6 mice during acute hepatitis caused by LCMV-WE infection. (E) Increased expression of DAP12 RNA in infected livers of C57BL/6 mice during acute hepatitis caused by LCMV-WE infection. (F) Increased alanine aminotransferase (ALT) concentrations in blood plasma of C57BL/6 mice during acute hepatitis caused by LCMV-WE infection. *p < 0.05, **p < 0.01.