Table 2.

Serum copper and 24 h urine copper in 38 patients with Wilson’s disease during treatment.

Group		First course			Second course			1 year
		Baseline	2 weeks	4 weeks	6 months	2 weeks	4 weeks
1	Serum copper	0.24 ± 0.04	0.23 ± 0.03	0.20 ± 0.05	0.23 ± 0.06	0.23 ± 0.08	0.21 ± 0.08	0.20 ± 0.04
	Urine copper	156.7 ± 121.9	1149.7 ± 202.9**	856.3 ± 312.7**	131.3 ± 89.5	1084.7 ± 393.6**	712.4 ± 451.9**	119.3 ± 78.5
	Patients (n)	21	21	21	21	21	21	21
2	Serum copper	0.25 ± 0.06			0.24 ± 0.04			0.22 ± 0.07
	Urine copper	163.7 ± 1054			121.1 ± 77.4			131.9 ± 93.5
	Patients (n)	17			17			17

Serum copper (mg/liter); urine copper (μg). First course: sodium dimercaptopropanesulfonate and zinc; second course: zinc.

^*p < 0.05; **p < 0.01.