Table 2.
Primary outcomes at 6 and 12 months in control and intervention groups
| Outcomes | Change from baseline | Adjusteda mean difference (95 % CI) | Effect size (95 % CI) | p value | |
|---|---|---|---|---|---|
| Usual care | CARE Plus | ||||
| Primary outcomes: | |||||
| 6 months | |||||
| EQ5D-5 L | −0.08 (0.27) | 0.04 (0.25) | 0.13 (0.01, 0.25) | 0.38 (0.00, 0.75) | 0.039 |
| W-BQ12 General Well-being | −1.3 (5.1) | −0.2 (6.5) | 0.70 (−2.45, 3.85) | 0.08 (−0.28, 0.44) | 0.66 |
| W-BQ12 Negative Well-being | 1.0 (2.8) | 0.0 (2.9) | −0.69 (−1.63, 0.24) | 0.18 (−0.06, 0.42) | 0.14 |
| W-BQ12 Energy | 0.7 (2.8) | 0.2 (2.7) | −0.42 (−1.85, 1.01) | −0.15 (−0.65, 0.36) | 0.56 |
| W-BQ12 Positive Well-being | −0.9 (2.8) | −0.5 (3.5) | 0.66 (−0.31, 1.64) | 0.18 (−0.09, 0.46) | 0.18 |
| 12 months | |||||
| EQ5D-5 L | −0.02 (0.28) | 0.02 (0.26) | 0.06 (−0.02, 0.14) | 0.14 (−0.10, 0.39) | 0.15 |
| W-BQ12 General Well-being | −1.6 (5.6) | 0.4 (6.8) | 1.99 (−0.27, 4.24) | 0.23 (−0.03, 0.49) | 0.083 |
| W-BQ12 Negative Well-being | 1.2 (2.8) | −0.2 (2.5) | −1.30 (−2.16, −0.43) | 0.33 (0.11, 0.55) | 0.0036 |
| W-BQ12 Energy | 0.6 (2.4) | 0.6 (2.9) | 0.31 (−0.55, 1.17) | 0.11 (−0.20, 0.42) | 0.47 |
| W-BQ12 Positive Well-being | −0.8 (3.3) | −0.6 (3.8) | 0.57 (−0.56, 1.70) | 0.16 (−0.16, 0.48) | 0.32 |
aMean differences were adjusted for baseline score, age, gender and Hospital Anxiety and Depression Scale caseness - positive effects sizes indicate a difference in favour of the intervention group.
CI confidence interval