Table 1.

Staging of CML that we use in our practice

Chronic phase

None of the criteria for accelerated or blastic phase

Accelerated phase

Blasts ≥ 15% in blood or BM

Blasts plus progranulocytes ≥ 30% in blood or BM

Basophilia ≥ 20% in blood or BM

Platelets < 100 × 109/L unrelated to therapy

Cytogenetic clonal evolution

Blast phase

≥ 30% blasts in blood or BM

Extramedullary disease with localized immature blasts