Table 5.
Response | Imatinib resistant |
Imatinib intolerant |
Total |
|||
---|---|---|---|---|---|---|
No. | % | No. | % | No. | % | |
Cumulative response* | ||||||
Patients in subgroup analysis | 55 | 23 | 78 | |||
Major | 35 | 64 | 15 | 65 | 50 | 64 |
Complete | 27 | 49 | 14 | 61 | 41 | 53 |
Reason for exclusion from analysis | ||||||
No assessment† | 70 | 21 | 91 | |||
Did not achieve complete cytogenetic response | 75 | 44 | 119 |
Major molecular response = ≥ 3 log reduction from standardized baseline Bcr-Abl:Abl ratio. Complete molecular response = undetectable Bcr-Abl, with a sensitivity of ≥ 5 log. Molecular response was not assessed according to the International Scale.
Because of logistical constraints, 4 countries (China, India, Russia, and South Africa) did not evaluate molecular response.