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. 2011 Aug 24;118(17):4567–4576. doi: 10.1182/blood-2011-05-355594

Table 5.

Molecular response among patients achieving complete cytogenetic response

Response Imatinib resistant
Imatinib intolerant
Total
No. % No. % No. %
Cumulative response*
    Patients in subgroup analysis 55 23 78
    Major 35 64 15 65 50 64
        Complete 27 49 14 61 41 53
Reason for exclusion from analysis
    No assessment 70 21 91
    Did not achieve complete cytogenetic response 75 44 119
*

Major molecular response = ≥ 3 log reduction from standardized baseline Bcr-Abl:Abl ratio. Complete molecular response = undetectable Bcr-Abl, with a sensitivity of ≥ 5 log. Molecular response was not assessed according to the International Scale.

Because of logistical constraints, 4 countries (China, India, Russia, and South Africa) did not evaluate molecular response.