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Diagrammatic representation of the five families of MDR efflux pumps in bacteria are the resistance nodulation division (RND) family, the major facilitator superfamily (MFS), and the staphylococcal multiresistance (SMR), and multidrug and toxic compound extrusion (MATE) families. A role for ABC (ATP binding cassette) MDR transporters in MDR of clinically relevant bacteria has yet to be established (Piddock, 2006). Reproduced with permission.
