Table 1.
Gene name | No. of cases with more than 3-fold up-regulation | Mean up-regulation in 9 samples, fold change |
---|---|---|
CCL4 | 7 | 10.16 |
TNFRSF17 | 7 | 6.72 |
EGR3 | 7 | 5.97 |
CCL3 | 6 | 6.09 |
PSAT1 | 6 | 4.98 |
MYCN | 6 | 4.96 |
EGR2 | 6 | 4.84 |
KIAA0101 | 6 | 4.39 |
KMO | 6 | 3.93 |
FCRL5 | 6 | 3.31 |
This table displays, in descending order, the top 10 genes up-regulated in CLL cells after coculture with NLCs. The left column displays the gene names. The middle column displays the number of CLL paired specimens that displayed a more than 3-fold gene up-regulation (of a total of 9 cases). The right column indicates the mean up-regulation of the genes in all 9 cases.
CCL4 indicates CC chemokine; TNFRSF17, B-cell maturation antigen (BCMA); EGR3, early growth response protein 3 gene; CCL3, CC chemokine; PSAT1, phosphoserine aminotransferase 1; MYCN, N-myc proto-oncogene; EGR2, early growth response protein 2 gene; KIAA0101, uncharacterized gene sequence; KMO, kynurenine 3-hydroxylase; and FCRL5, Fc receptor-like 5.