Figure 2. The suppressive effects of HES are not due to antigen competition.
20 μg HES or Bovine Serum Albumin (BSA) were coadministered with each sensitisation injection of OVA-Alum on d0 and d14, and following challenge at days 28-30, bronchoalveolar lavage (BAL) fluid and serum were collected at day 31. Shown are: (A) the total BAL cell numbers, (B) the SiglecF+CD11c- (eosinophil) proportion of total BAL cells, (C) the SiglecF+CD11c- (eosinophil) BAL cell numbers, (D) OVA-specific IgG1 measured by ELISA and (E) the OVA-specific IgE measured by ELISA. Results are representative of 2 repeat experiments each with 4-6 mice per group. Error bars are SEM. ***p<0.001, one-way ANOVA, with a Tukey’s post test.