Figure 5.

Ex vivo fluorescence imaging of specimens from lung cancer patients. (A) White light and fluorescence images of lung cancer specimens. A total of 50 µM gGlu-HMRG was applied to lung tumor and normal lung tissue, and images were captured before and 5, 10, and 30 minutes after by Maestro with appropriate exposure time. Fluorescence image at 540 nm was extracted. Fluorescence intensity of the lung tumor was increasing in case 1 and 2, but not in case 3. (B) Fluorescence intensity values of lung tumor and normal lung in case 1, 2, and 3 were calculated. Fluorescence intensity gradually increased in case 1 and 2, but not in case 3.