Table 1. Elapsed time for calculating MICs for different sample sizes.

	Number of samples	100	1000	2000	4000	10000	20000
Independent variable pair	ChiMIC (second)	0.0046±5e-04	0.1520±0.03	0.537±0.11	2.166±0.59	12.93±4.1	53.55±11
	ApproxMaxMI(second)	0.0061±6e-04	0.5229±0.02	2.188±0.24	8.502±0.12	60.02±0.8	284.38±11
Parabolic function (noise_LEVEL = 0.4)	ChiMIC (second)	0.0021±3e-04	0.1325±0.02	0.5946±0.12	2.754±0.45	21.41±3.5	99.70±10
	ApproxMaxMI(second)	0.0021±5e-04	0.1407±0.03	0.7360±0.15	3.523±0.54	26.65±2.1	122.8±12

The corresponding time was represented as the average value ± standard deviation over 100 time replicated runs on a Windows 7 32-bit operating system (RAM: 3.00GB, CPU: 2.80 GHz).