Table 4. The association between diabetes mellitus and original scores of QOL among breast cancer survivors.
(Original scores, (MeanDMi-Mean No DM)(MeanDMi±SD)).
| DM,n = 614 | T1DM,n = 131 | T2DM,n = 483 | ||
|---|---|---|---|---|
| No DM,n = 5574 | No DM,n = 5574 | No DM,n = 5574 | ||
| EORTC QLQ-C30 | ||||
| Global health status | QL | -3.0(64.3±23.1) ** | -1.3(65.7±24.1) | -2.8(64.4±22.5) * * |
| Physical functioning | PF | -2.6(82.4±14.9) *** | -2.4(82.4±15.2) * | -2.5(82.4±15.5) *** |
| Role functioning | RF | -1.3(89.3±19.1) | -1.1(89.4±18.7) | -1.2(89.4±18.4) |
| Cognitive functioning | CF | -1.8(79.5±18.7) * | -3.6(77.6±18.8) ** | -0.7(80.5±17.8) |
| Emotional functioning | EF | -1.7(83.2±18.0) * | -3.3(81.5±19.7) ** | -1.0(83.8±17.5) |
| Social functioning | SF | -1.4(80.9±21.9) | -2.3(79.9±23) | -1.7(80.6±22.6) |
| Fatigue | FA | 2.2(26.9±18.8) ** | 2.2(27.0±19.2) * | 1.6(26.4±18.0) |
| Nausea and vomiting | NV | 0.8(3.5±10.8) * | 1.8(4.5±11.8) ** | -0.2(2.6±8.4) |
| Pain | PA | 2.6(17.7±18.3) *** | 3.7(18.9±18.8) ** | 2.0(17.3±18.1) ** |
| Dyspnoea | DY | 4.4(16.9±22.1) *** | 4.5(17.3±21.6) *** | 3.8(16.4±21.6) *** |
| Insomnia | SL | 3.9(22.5±25.0) *** | 4.2(23.1±24.8) ** | 3.1(21.9±25.9) ** |
| Appetite loss | AP | 1.0(7.6±15.7) | 0.9(7.5±16.3) | 0.9(7.6±16.5) |
| Constipation | CO | 3.3(12.2±20.7) *** | 0.7(9.9±19.4) | 3.1(12.0±20.5) *** |
| Diarrhoea | DI | 2.7(9.7±18.4) *** | 4.0(11.1±18.6) *** | 1.8(8.9±17.9) * |
| Financial difficulties | FI | 3.8(31.0±32.3) ** | 4.7(32.1±32.5) | 4.3(31.6±33.1) ** |
| QLQ-BR23 | ||||
| Body image | BRBI | -2.9(64.1±25.8) ** | -2.7(64.1±25.5) * | -2.3(64.6±25.7) * |
| Sexual functioning | BRSEF | -2.9(95.0±13.0) *** | -2.1(94.3±13.1) | -3.4(95.4±12.1) *** |
| Sexual enjoyment | BRSEE | -4.4(95.1±13.6) *** | -3.5(94.6±13.2) | -4.9(95.7±12.5) *** |
| Future perspective | BRFU | -4.9(58.0±32.9) *** | -3.2(59.3±33.1) | -4.9(57.9±33.5) ** |
| Side effects | BRST | 3.7(19.4±13.1) *** | 3.9(19.8±13.5) *** | 3.4(19.2C13.4) *** |
| Breast symptoms | BRBS | 4.5(20.8±20.8) *** | 5.4(21.9±20.2) *** | 3.9(20.3±20.8) *** |
| Arm symptoms | BRAS | 3.6(25.5±22.2) *** | 3.9(26.0±21.2) * | 3.5(25.5±22.8) *** |
| Upset by hair loss | BRHL | 3.3(21.5±27.3) ** | 2.7(21.1±25.9) | 3.4(21.7±28.1) ** |
1. DM, contained T1DM and T2DM; 2.Original scores, (MeanDMi-Mean No DM)(MeanDMi ±SD): The difference value between mean score of quality of life instrument with having diabetes and having no it. (mean score of quality of life instrument with having diabetes). 3.* P <0.05, ** P <0.01, *** P <0.001.