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. Author manuscript; available in PMC: 2016 Jun 22.
Published in final edited form as: J Med Chem. 2007 Aug 14;50(18):4340–4350. doi: 10.1021/jm061288r

Scheme 3.

Scheme 3

Synthesis of Monoalkyl and Dialkyl N-Substituted KF Based on Stepwise Reductive Alkylation in the Presence of a Carboxaldehyde and Triacetoxyborohydridea

a Reagents and conditions: aldehydes, Na(OAc)3BH, MeOH, 3 Å molecular sieves, room temp.