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Amidation Reaction of Kahalalide F and DEAC Acid in the Presence of a Coupling Agenta
a Reagents and conditions: O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate (HBTU), N-ethyl-N′-(3-dimethylaminopropyl)carbodiimide (EDC), DMF, room temp, 1 h, 84.9%.
