Table 4.
Microtiter Analysis of Kahalalide Analogues at Different Concentrations (48 and 72 h)
| % inhibitiona (0.3 µM) | % inhibitiona (3.0 µM) | % inhibitiona (30 µM) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| compd |
Fusarium oxysporum |
Fusarium proliferatum |
Fusarium solani |
Fusarium oxysporum |
Fusarium proliferatum |
Fusarium solani |
Fusarium oxysporum |
Fusarium proliferatum |
Fusarium solani |
| 1 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 9.9 (0) | 100 (99.6) | 99.8 (100) | 98.9 (99.9) |
| 3 | 0 (0) | 0 (0.3) | 0 (0) | 0 (0) | 0 (0.3) | 0 (0) | 78.5 (74.4) | 70.8 (34.7) | 80.9 (96.7) |
| 4 | 1.8 (0) | 1.8 (0) | 0 (0) | 1.8 (0) | 5.0 (0) | 0 (0) | 91.9 (82.2) | 92.7 (73.2) | 90.6 (85.5) |
| 5 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 16.5 (0) | 96.6 (94.3) | 97.5 (96.1) | 97.3 (97.3) |
| 7 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 98.2 (91.2) | 99.1 (95.3) | 99.2 (97.5) |
| 8 | 0 (0) | 0 (0) | 0 (0) | 13.7 (0) | 4.8 (0) | 47.0 (32.9) | 98.8(99.2) | 98.7 (99.0) | 99.0 (99.3) |
| 10 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 93.6 (89.0) | 95.3 (92.8) | 94.3 (94.7) |
| 16 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| azoxystrobin | 22.7(15.3) | 0 (0) | 16.6 (11.7) | 32.3 (7.1) | 21.7 (14.8) | 25.3 (15.0) | 77.2 (32.9) | 53.0 (40.7) | 62.7 (51.7) |
| captan | 0.2 (0) | 6.0 (3.0) | 0 (0) | 7.6 (0) | 12.0 (0) | 5.1 (0) | 99.5 (98.1) | 100 (100) | 90.7 (47.9) |
| amphotericin B | 0 (0) | 0 (0) | 0 (0.1) | 12.5 (0) | 7.9 (0) | 18.1 (0) | 99.7 (87.1) | 99.8 (79.0) | 100 (98.1) |
a
Sample results only indicate inhibition. Zero (0) does not indicate the degree of stimulation, only that there was no inhibition. Numbers above are 48 h results. Numbers enclosed in parentheses are 72 h results.