Fig. 3.

Comparison of cerebrovascular metrics in regions of pre-existing and future WMHs. All values are given as % change from contralateral NAWM and assessed on baseline MRI scans. Values for future WMHs are made in the NAWM on the baseline scan (before the progression into overt WMH). ssCVR are significantly lower and τ is significantly higher in pre-existing and future WMHs compared to NAWM. * denotes significance compared to NAWM (P < 0.01). Bars indicate minimum and maximum, boxes indicate the interquartile range (25th to 75th percentile) and the line within each box indicates the median.