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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: J Heart Lung Transplant. 2016 Feb 8;35(6):777–788. doi: 10.1016/j.healun.2016.01.1222

Table 4.

Factors Associated with Change in HRQOL Pre-implant – 6 months post implant

Risk Factors Estimates (SE) p value
Pre-implant conditions
 INTERMACS Level 1   5.1 (1.6)   0.002
 BTT: Listed −3.7 (1.2)   0.002
 Pre COPD −10.4 (2.67)   0.0001
 Ascites −3.7 (2.3)   0.10
 Alcohol abuse −4.4 (1.7)   0.01
 Pre-implant VAS Score −0.78 (0.02) < 0.0001
 COPD * Pre-implant VAS score interaction   0.17 (0.06)   0.008
Clinical Course
 BTT: Unlikely at 6 months −9.9 (2.9)   0.0006
 BTT: Mod likely at 6 months −4.7 (1.9)   0.01
 NYHA 4 at 6 months −15.3 (2.9) < 0.0001
Events within first 6 months
 Renal Dysfunction −5.3 (2.5)   0.03
 Respiratory Failure −4.8 (1.8)   0.008
 Neurological Dysfunction −5.6 (1.9)   0.004
 Infection −2.8 (1.1)   0.01

Intercept = 65.0, R2 = 41% n=2748, p < 0.0001

HRQOL=health-related quality of life; INTERMACS=interagency Registry for Mechanically Assisted Circulatory Support; BTT=bridge to transplant; COPD=chronic obstructive pulmonary disease; VAS=visual analog scale

Negative coefficients indicate the decrement in change

The Intercept indicates the amount of change (improvement) for a patient with no ‘risk factors’