Table 4.
Risk Factors | Estimates (SE) | p value |
---|---|---|
Pre-implant conditions | ||
INTERMACS Level 1 | 5.1 (1.6) | 0.002 |
BTT: Listed | −3.7 (1.2) | 0.002 |
Pre COPD | −10.4 (2.67) | 0.0001 |
Ascites | −3.7 (2.3) | 0.10 |
Alcohol abuse | −4.4 (1.7) | 0.01 |
Pre-implant VAS Score | −0.78 (0.02) | < 0.0001 |
COPD * Pre-implant VAS score interaction | 0.17 (0.06) | 0.008 |
Clinical Course | ||
BTT: Unlikely at 6 months | −9.9 (2.9) | 0.0006 |
BTT: Mod likely at 6 months | −4.7 (1.9) | 0.01 |
NYHA 4 at 6 months | −15.3 (2.9) | < 0.0001 |
Events within first 6 months | ||
Renal Dysfunction | −5.3 (2.5) | 0.03 |
Respiratory Failure | −4.8 (1.8) | 0.008 |
Neurological Dysfunction | −5.6 (1.9) | 0.004 |
Infection | −2.8 (1.1) | 0.01 |
Intercept = 65.0, R2 = 41% n=2748, p < 0.0001
HRQOL=health-related quality of life; INTERMACS=interagency Registry for Mechanically Assisted Circulatory Support; BTT=bridge to transplant; COPD=chronic obstructive pulmonary disease; VAS=visual analog scale
Negative coefficients indicate the decrement in change
The Intercept indicates the amount of change (improvement) for a patient with no ‘risk factors’