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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Biomol Screen. 2016 Feb 8;21(6):643–652. doi: 10.1177/1087057116629381

Figure 3. Biochemical profiling of isoform selectivity of histone deacetylase (HDAC) inhibitor hits.

Figure 3

In total, 20 μM of the 15 selected potential HDAC inhibitors were tested with individual recombinant HDAC class I and II enzymes and their corresponding fluorogenic substrates. Efficacy values were averaged from three replicates and shown in heat map.