Table 3.
Predictors of HCC in Veterans with HCV who achieved an SVR. Results from Cox proportional hazards model while adjusting for the competing risk of death.
| variable | level | Hazard Ratio (95% CI) | p-value |
|---|---|---|---|
| Diabetes (time-varying) | no | 1.0 (ref) | |
| yes | 1.876 (1.211 – 2.906) | 0.0048 | |
| Race | White | 1.0 (ref) | |
| Black | 1.398 (0.730 – 2.679) | 0.3121 | |
| Hispanic | 2.269 (1.073 – 4.798) | 0.0319 | |
| Asian | 3.016 (0.411 – 22.138) | 0.2777 | |
| Other | 1.684 (0.231 – 12.248) | 0.6069 | |
| Missing | 1.301 (0.716 – 2.362) | 0.3875 | |
| Cirrhosis at SVR | no | 1.0 (ref) | |
| yes | 6.686 (4.319 – 10.350) | <.0001 | |
| Alcohol | no | 1.0 (ref) | |
| yes | 1.676 (1.082 – 2.595) | 0.0207 | |
| Age at SVR | < 45 | 0.559 (0.133 – 2.345) | 0.4269 |
| 45 – 54 | 1.0 (ref) | ||
| 55 – 64 | 2.043 (1.292 – 3.231) | 0.0023 | |
| 65+ | 4.509 (1.955 – 10.400) | 0.0004 | |
| HCV genotype | 1 | 1.0 (ref) | |
| 2 | 0.591 (0.324 – 1.077) | 0.0859 | |
| 3 | 1.620 (0.960 – 2.734) | 0.0709 |
CI: confidence intervals; SVR: sustained virological response