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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Brain Behav Immun. 2016 Mar 2;56:209–220. doi: 10.1016/j.bbi.2016.02.025

Fig. 3. The blockade of (i) GRs by RU486, (ii) β-adrenoceptors and GRs by nadolol and RU, and (iii) opioid receptors by naltrexone did not prevent the deleterious effects of stress on the efficacy of CpG-C treatment.

Fig. 3

CpG-C decreased MADB106 LTR levels in the absence of stress (HCC) (*), and Wet cage stress exposure prevented this beneficial effect. The use of the GR blocker RU486 alone (a), the GR blocker RU with the β-adrenoceptor antagonist nadolol (b), or the opioid receptor antagonist naltrexone (c), did not prevent the effects of stress. * indicates a significant difference from PBS at p < 0.05. Data is shown as mean ± SEM.