Group comparisons on whole-brain network characteristics. No significant differences between AD group and matched HCs on whole-brain network topology, expressed as clustering coefficient (t = 0.4219, P = 0.6754), degree (t = 0.3837, P = 0.7006), eigenvector centrality (t = −0.8284, P = 0.4125) and global efficiency (t = −0.0079, P = 0.9937). All analyses were corrected for age, gender and head motion. Abbreviations: AD, alcohol dependent group; HC, healthy control group