Table 2.
Relevant pathways modulated by 5-FU + OXP + FA treatment (p < 0.01).
| Pathway name | p-value | Matched entities | Total pathway entities |
|---|---|---|---|
| Hs_AMPK_Signaling_WP1403_79471 | 8.28E-11 | 45 | 68 |
| Hs_Apoptosis_Modulation_and_Signaling_WP1772_80459 | 2.42E-08 | 52 | 95 |
| Hs_Apoptosis_WP254_80450 | 4.17E-09 | 50 | 87 |
| Hs_Benzo(a)pyrene_metabolism_WP696_72081 | 0.0090 | 6 | 9 |
| Hs_DNA_Damage_Response_WP710_79974 | 8.78E-09 | 62 | 114 |
| Hs_DNA_Damage_Reversal_WP1804_83251 | 0.0089 | 5 | 6 |
| Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 | 3.82E-09 | 82 | 162 |
| Hs_Fluoropyrimidine_Activity_WP1601_82222 | 2.16E-07 | 24 | 34 |
| Hs_Folate-Alcohol_and_Cancer_Pathway_WP1589_82223 | 0.00901 | 6 | 8 |
| Hs_Gastric_Cancer_Network_1_WP2361_84551 | 3.62E-06 | 20 | 29 |
| Hs_Integrated_Cancer_Pathway_WP1971_82939 | 4.51E-05 | 26 | 49 |
| Hs_MAPK_Signaling_Pathway_WP382_79951 | 3.84E-11 | 89 | 168 |
| Hs_Oncogene_Induced_Senescence_WP3308_83246 | 0.0098 | 12 | 26 |
| Hs_Oxidative_Stress_Induced_Senescence_WP3404_83222 | 7.05E-07 | 49 | 99 |
| Hs_Oxidative_Stress_WP408_78546 | 3.54E-04 | 18 | 30 |
| Hs_Senescence_and_Autophagy_in_Cancer_WP615_81193 | 5.87E-04 | 47 | 109 |
The matched entity value represents the total number of genes differentially expressed in a pathway in given experimental conditions compared with the total number of entities of the pathway in the database.