Fig. 1.

Relationship between body weight loss and change of MDASI-J score. Increase in score change indicates worsening of quality of life (QOL). Four hundred six patients were divided into four groups equally according to percentage of body weight (BW) loss from baseline. First quartile includes patients with BW loss ≤2.3 %; second quartile, BW loss 2.3 % ≤6.1 %; third quartile, BW loss 6.1 % ≤10.9 %; and fourth quartile, BW loss >10.9 %. QOL was evaluated and scored using MDASI-J questionnaire. Regression coefficient was −0.0291 (P = 0.0002) with linear regression analysis. MDASI-J, the Japanese version of the M.D. Anderson Symptom Inventory