Table 1.
Balloon | Material | Volume | Weight loss1 | Note |
Fluid-supplied | ||||
Orbera (Apollo Endosurgery) | Silicone | 400-700 mL (saline) | 16.9 ± 0.9 kg (at 6 mo)[58] | Most widely used and studied intragastric balloon |
Volume adjustment at the time of placement | ||||
Spatz Adjustable Balloon system (Spatz FGIA) | Silicone | 400-600 mL (saline) | 24 kg (at 12 mo)[64] | Totally adjustable balloon |
Approved for 12 mo of implantation | ||||
ReShape Duo® Integrated DualBalloon System (ReShape medical) | Silicone | 900 mL (450 mL × 2) (saline) | 25.1 ± 1.6 %EWL (at 6 mo)[62] | Two independent balloons connected to silicone shaft |
The Elipse™ (Allurion Technologies) | N/A | 450-550 mL (filling fluid) | 2.4 kg (at 6 wk)[19] | Naturally swallowed, self-emptying, and naturally excreted |
Air-supplied | ||||
Obalon® Gastric Balloon (Obalon Therapeutics) | N/A | 250 mL (air, nitrogen) | 5 kg (at 12 wk)[66] | Can be swallowed |
A second or a third balloon can be swallowed depending on patient’s progress | ||||
Heliosphere BAG® (Helioscopie) | Polyurethane and silicone | 950 mL (air) | 16 ± 7 kg (at 6 mo)[23] | Less than 30 g |
Values extrapolated from representative reviews and clinical trials of each intervention. N/A: Not available; %EWL: Percentage of excess weight loss.