Table 1.

Main results from trials on Escherichia coli Nissle on ulcerative colitis

Efficacy of EcN 1917 in maintanance of UC remission
Results from major randomized controlled clinical trials
EcN 200 mg/d is equivalent to Mesalazine 1000 mg/d in mantainance of UC remission[27]
EcN 400 mg/d is equivalent to to Mesalazine 2400 mg/d in maintanance of UC remission following an acute flare[28]
EcN 200 mg/d is equivalent to Mesalazine 1500 mg/d in mantainance of UC remission[10]
Results from minor studies
Rectal admistration of EcN 40 mL/d is effective in moderate distal active UC[30]
EcN 200 mg/d is equivalent to Mesalazine 1500 mg/d in maintanance of UC remission[6]

EcN: Escherichia coli Nissle; UC: Ulcerative colitis.