Table 1.
Summarized information of selected single nucleotide polymorphisms in cell cycle pathway genes
| Genes | SNPs | Chromosome (position) | Allele | MAF (hapmap-HCB) |
| MCM4 | rs2305952 | 8 (47962049) | C/T | C = 0.18 |
| YWHAB | rs2425675 | 20 (44906293) | A/G | A = 0.20 |
| CDKN2A | rs3088440 | 9 (21968160) | A/G | A = 0.08 |
| TGFB3 | rs3917148 | 14 (75980178) | A/C | C = 0.10 |
| RBL2 | rs3929 | 16 (53490396) | C/G | C = 0.20 |
| RAD21 | rs6987652 | 8 (116870042) | A/G | A = 0.12 |
| SMAD3 | rs11556090 | 15 (67194045) | A/G | G = 0.09 |
| rs8025774 | 15 (67190938) | C/T | C = 0.45 | |
| KAT2B | rs17006625 | 3 (20119604) | A/G | G = 0.14 |
| rs4858770 | 3 (20152931) | C/T | T = 0.47 | |
| MCM7 | rs2070215 | 7 (100099174) | A/G | G = 0.29 |
| rs2261360 | 7 (100095370) | A/C | A = 0.37 | |
| CDKN1A | rs3176320 | 6 (36679011) | A/G | G = 0.17 |
| CDC25C | rs3734166 | 5 (138329634) | A/G | G = 0.38 |
| CHEK1 | rs515255 | 11 (125627250) | C/T | T = 0.44 |
MAF (minor allele frequency) was derived from HCB population in HapMap website (http://hapmap.ncbi.nlm.nih.gov/). SNPs: Single nucleotide polymorphisms.