Table 3.
Comparison of features between patients with mutations and polymorphisms
| Group 1 | Group 2 | |
| Size of sample | 5 | 8 |
| Age of onset (mo) | 2.7 | 7.7 |
| Height percentile | 5.0% | 15.6% |
| Weight percentilea | 1.0% | 27.5% |
| WBC (× 10-9) | 15.2 | 16.3 |
| Hemoglobin (g/L)a | 87.4 | 108.5 |
| Platelets (× 10-9) | 538.4 | 424.0 |
| C reactive protein (mg/L) | 60.7 | 35.9 |
| ESR (mm/H) | 32.2 | 16.6 |
| TNFα (pg/mL) | 44.5 | 51.6 |
| Diagnosis of CD | 100.0% | 62.5% |
| Recurrent infection | 80.0% | 25.0% |
| Perianal disease | 60.0% | 25.0% |
a
P < 0.05. All measurement data are expressed as mean. Group 1: Mutations in IL-10RA or IL-10RB; Group 2: Polymorphisms. Height and weight percentile was calculated according to WHO charts. WBC: White blood cell; ESR: Erythrocyte sedimentation rate; TNFα: Tumor necrosis factor alpha; CD: Crohn's disease.