Table 1. Overview of CPTI roles in cancer biology.

CPTI isoform	Cancer type	Significance	Reference
CPTIA	Prostate cancer	Upregulated expression; its inhibition has antitumor actions	25, 41, 50
	Burkitt's lymphoma	Upregulated expression	28
	Glioblastoma	Upregulated expression	29, 30
	Lymphocytic leukemia	Its inhibition has antitumor actions; contributes to cancer chemoresistance	7, 35, 42
	Breast cancer	Upregulated expression; its inhibition has antitumor actions; acts as a new role in the histonic acetylation level of tumor	37, 52, 53, 54, 55, 86
	Gastric cancer	Oleic acid activates its expression	55
	Ovarian cancer	Upregulated expression	56, 57
	Alveolar rhabdomyosarcoma	Contributes to cancer cell motility	74
	Teratocarcinoma	Transcriptional regulation of it by RXR-NR4A receptor	81
	Endothelial cells	Upregulated expression; contributes to tumor neovascularization	98, 99
CPTIC	Lung cancer	Upregulated expression contributes to cancer chemoresistance	18
	Colon	Its inhibition has antitumor actions	18
	Breast	Upregulated expression	18, 62
	Glioblastoma	Upregulated expression	29, 59
CPTI (unspecified isoform)	Hepatoma	Upregulated expression	58, 60
	Acute myeloid leukemia	Its inhibition has antitumor actions	63
	Diffuse large B-cell lymphoma	Upregulated expression	26, 27
	Myeloma	Its inhibition has antitumor actions	51
	Lung cancer	Contributes to cancer chemoresistance	34

Abbreviation: CPTI, carnitine palmitoyltransferase I