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. 2015 Nov 4;9(4):950–959. doi: 10.1038/mi.2015.108

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Copyright © 2016 Society for Mucosal Immunology

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Lower IL1R2 gene expression in UC patients who relapsed during the following year. (a) Intestinal mucosa IL1R2 gene expression by qPCR (-Delta Ct) from UC patients in remission (line as median). Patients were classified as Relapse (n=21) or No Relapse (n=24) patients according to whether or not they had a disease flare (confirmed by the presence of endoscopic lesions) at some point during their 1-year follow-up. Gene expression data were analyzed by a Mann–Whitney test. *P<0.05. (b) IFNG and IL1R2 expression correlation in UC patients in remission that relapsed within the following year. Spearman correlation was performed *P<0.05 (Pearson r −0.5336). IL, interleukin; qPCR, quantitative real-time RT-PCR; UC, ulcerative colitis.