Gene expression changes induced by SAHA were confirmed by RT-qPCR in the same RNA samples used for microarray analysis (Donors 1–6). RT-qPCR analysis was also used to confirm expression changes for the six most strongly SAHA dose-responsive genes in primary CD4+ T cells used in ChIP analysis (Donors 7–9). (a) The top 3 dose-responsive upregulated genes, and (b) the top 3 dose-responsive downregulated genes. Abbreviations are as follows: CTNNAL1, catenin (cadherin-associated protein), alpha-like 1; H1f0, H1 histone family, member 0; IRGM, immunity-related GTPase family, M; DPEP2, Dipeptidase 2; PHF15, PHD finger protein 15; SELL, Selectin L