Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IL-1β levels are ablated in macrophages harvested from Casp11 −/− and Asc −/− mice following ex vivo infection with Toxoplasma gondii. Bone marrow derived macrophages were primed with 100 ng/mL of LPS for 30 mins prior to stimulation with either Toxoplasma gondii Me49 (MOI = 1) or vehicle for 24 hrs. IL-1β levels in cell-free supernatants were quantified using ELISA. ∗ p < 0.05; ∗∗ p < 0.01. Data shown are representative of 3 independent experiments utilizing 2 mice per genotype.
