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. 2016 Apr 25;82(1):185–198. doi: 10.1111/bcp.12934

Figure 2.

Figure 2

Simulated mid‐dose concentrations across weight‐bands (left) and by different 516GT|983TC genotypes (right) based on suggested most optimal dosing. Red horizontal lines correspond to efavirenz concentrations of 1 mg l−1 and 4 mg l−1 3. Breaks in the percentile plot correspond to 25th, median and 75th percentile and whiskers correspond to 5th and 95th percentile of the simulated data. CYP2B6 (Inline graphic) 516GG|983TT; (Inline graphic) 516GG|983TC; (Inline graphic) 516GG|983CC; (Inline graphic) 516GT|983TT; (Inline graphic) 516GT|983TC; (Inline graphic) 516TT|983TT