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. 2016 Jun 23;6:28580. doi: 10.1038/srep28580

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(a) LPS-treated bipolar/rod-shaped microglia transformed into amoeboid microglia in 30 minutes and maintained this morphology for a few hours. (b) LPS induced an increased in mRNA expression of Adam9 and Ctss in the amoeboid microglia transformed from bipolar/rod-shaped microglia at 6 hours after culture on scratched PDL/laminin-coated culture dishes (n = 4). (c) LPS did not induce any change in the mRNA expression of Adam9 and Ctss in amoeboid microglia at 6 hours after culture on non-scratched PDL/laminin-coated culture dishes (n = 4). *P < 0.05, Student’s t-test.