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. 2016 Jun 23;6:28580. doi: 10.1038/srep28580

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Copyright © 2016, Macmillan Publishers Limited

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Trains of bipolar/rod shaped microglia could not be maintained and stabilized on scratched culture dishes without a PDL/laminin coating. The scratched area of a PDL/laminin-coated surface supports stable bipolar/rod-shaped microglia trains. Adam9 and Ctss up-regulation in both amoeboid-enriched and amoeboid microglia that were transformed from bipolar/rod shaped microglia is likely associated with laminin degradation and cell motility.