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. 2016 Jun 23;6:28530. doi: 10.1038/srep28530

Table 4. Haplotype association of SNPs in WNT pathway and tuberculosis.

Gene Haplotypea Frequency
OR (95% CI) P P**
All TB HC
CTNNB1 CGG 0.764 0.785 0.748 1.00    
  GCA 0.212 0.175 0.240 0.69 (0.600.83) 5.85 × 10−4 0.016
WNT5A AAC 0.617 0.614 0.619 1.00    
  CGG 0.359 0.366 0.354 1.03 (0.90–1.17) 0.700  
  CAC 0.014 0.019 0.010 2.04 (1.15–3.62) 0.054  
WNT1 CC 0.502 0.496 0.508 1.00    
  TT 0.475 0.480 0.47 1.01 (0.89–1.15) 0.840  
  CT 0.023 0.024 0.022 1.13 (0.73–1.76) 0.590  
WIF1 CC 0.819 0.830 0.811 1.00    
  GG 0.175 0.126 0.185 0.88 (0.74–1.03) 0.120  

P**: p value after Bonferroni correction.

aHaplotype frequency <0.01 in both cases and controls has been dropped; significant associations were denoted in bold. Wild haplotype was set as the reference, and the OR of other haplotypes were calculated.