Table 8.

Analysis of percentage of CFS/ME patients improving ET by at least 25% and 50% from baseline [43].

	% of Patients (n) improving
Percent improvement	Rintatolimod	Placebo	p-valuea
A. Intention to treat (ITT) population (n = 208)
≥25%	39% (n = 39)	23.1% (n = 25)	0.013
≥50%	26% (n = 26)	13.9% (n = 15)	0.028
B. Subsets of ITT population with baseline ET>9 minutes (n = 126)
≥25%	33.3% (n = 20)	12.1% (n = 8)	0.004
≥50%	23.3% (n = 14)	4.5% (n = 3)	0.003

^aProbability values derived from the Chi-square test or Fisher’s Exact Test if any cell had less than 5 observations.