Table 12.
Species | Maximum tolerated dose |
---|---|
Rabbit | 1.25 mg/kg/dose |
Dog | 10 mg/kg/dose |
Rat | 12.5 mg/kg |
Cynomolgus monkey | 100 mg/k g |
aThe MTD is defined as the highest dose with no observed mortality or moribund toxicity.
Species | Maximum tolerated dose |
---|---|
Rabbit | 1.25 mg/kg/dose |
Dog | 10 mg/kg/dose |
Rat | 12.5 mg/kg |
Cynomolgus monkey | 100 mg/k g |
aThe MTD is defined as the highest dose with no observed mortality or moribund toxicity.